Jason Cohen puts his finger on the problem with the recently announced and, since, much quoted, Startup Genome Project:
Macro-level data are useful for trends but not for understanding individual outcomes. Startup Genome conclusions are fascinating as high-level trends and certainly suggest possible behavior, but (...) it often doesn't apply.
Jason goes on to point out other problems with the rules amassed by the Startup Genome Project team, and also includes a response from Ron Berman. Worth a read.
I find the Startup genome Project interesting, but I agree with Jason that it shouldn't be used as a guide to how to run your startup, any more than the world height statistics should be used as a guide to whether you should enter a tunnel with a 1m90 high ceiling.